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Cancer
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CXCL8 (IL-8) is a member of the cancer-related chemokine cluster and is upregulated by TNFa on MCF-7 cells [1].
Cancer References1. Leibovich-Rivkin, Tal, et al. "The inflammatory cytokine TNFalpha cooperates with Ras in elevating metastasis and turns WT-Ras to a tumor-promoting entity in MCF-7 cells." BMC cancer 14.1 (2014): 158. Article Link
2. Sunaga N, Imai H, Shimizu K, Shames DS, Kakegawa S, Girard L, Sato M, Kaira K, Ishizuka T, Gazdar AF, Minna JD, Mori M. "Oncogenic KRAS-induced interleukin-8 overexpression promotes cell growth and migration and contributes to aggressive phenotypes of non-small cell lung cancer." Int J Cancer 2012, 130(8):1733-1744. PubMed Abstract | Publisher Full Text |PubMed Central Full Text 3. Carlos Eduardo Coral de Oliveira, Julie Massayo Maeda Oda, Roberta Losi Guembarovski, et al., “CC Chemokine Receptor 5: The Interface of Host Immunity and Cancer,” Disease Markers, vol. 2014, Article ID 126954, 8 pages, 2014. doi:10.1155/2014/126954 Article Link |
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