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  • CXCL12 (SDF-1α)

CXCL12 (SDF-1α)

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Stromal-Cell Derived Factor-1α (SDF-1α) (CXCL12) attracts lymphocytes and plays important roles in embryogenesis and angiogenesis with implications in tumor metastasis. By binding to CXCR4, one of the co-receptors for HIV viral entry, SDF-1α can suppress HIV. Besides CXCR4, SDF-1α also binds to the “decoy” receptor CXCR7, and activates the downstream β-arrestin- rather than G protein-mediated signaling pathway.
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ChemoTactics, Inc. 
6076 Corte Del Cedro
Carlsbad, CA 92011 USA

Phone: (858)-412-0485

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