Recombinant Biotinylated Chemokine Proteins from ChemoTactics
  • Chemokine Products
    • Biotinylated Chemokines >
      • Biotinylated CCL2 (MCP-1)
      • Biotinylated CCL3 (MIP-1α)
      • Biotinylated CCL4 (MIP-1β)
      • Biotinylated CCL5 (Rantes)
      • Biotinylated CCL7 (MCP-3)
      • Biotinylated CCL14 (HCC-1)
      • Biotinylated CCL19 (MIP-3β)
      • Biotinylated CCL28 (MEC)
      • Biotinylated CXCL8 (IL-8)
      • Biotinylated CXCL12 (SDF-1α)
    • Unmodified Chemokines >
      • CCL2 (MCP-1)
      • CCL3 (MIP-1α)
      • CCL4 (MIP-1β)
      • CCL5 (RANTES)
      • CCL7 (MCP-3)
      • CCL14 (HCC-1)
      • CCL19 (MIP-3β)
      • CCL27 (CTACK)
      • CCL28 (MEC)
      • CXCL8 (IL-8)
      • CXCL10 (IP-10)
      • CXCL12 (SDF-1α)
  • Streptavidin Conjugates
  • Services
  • Resources
    • Published Applications Biotinylated CXCL12 and CCL5
    • What are Chemokines?
    • Chemokine Protocols >
      • Flow Cytometry with Biotinylated Chemokines
      • ELISA with Biotinylated Chemokines
      • Transwell Migration Assay
    • Blog
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High-Quality Chemokine Protein Reagents 

ChemoTactics produces and validates high-quality recombinant chemokine proteins for research use. ​
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Biotinylated ​Chemokines
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  • CCL2 (MCP-1)-Biotin
  • CCL3 (MIP-1a)-Biotin
  • CCL4 (MIP-1B)-Biotin
  • CCL5 (Rantes)-Biotin
  • CCL7 (MCP-3)-Biotin
  • CCL14 (HCC-1)-Biotin
  • CCL19 (MIP-3B)-Biotin
  • CCL28 (MEC)-Biotin
  • CXCL8 (IL-8)-Biotin
  • CXCL12 (SDF-1a)-Biotin
Unmodified Chemokines​
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  • CCL2 (MCP-1)
  • CCL3 (MIP-1a)
  • CCL4 (MIP-1B)
  • CCL5 (Rantes)
  • CCL7 (MCP-3)
  • CCL14 (HCC-1)
  • CCL19 (MIP-3B)
  • CCL27 (CTACK)
  • CCL28 (MEC)
  • CXCL8 (IL-8)
  • CXCL10 (IP-10)
  • CXCL12 (SDF-1a)
We specialize in producing biotinylated chemokines for various applications and assay design.
​We also now provide streptavidin fluorescent conjugates. Contact us for more info. 
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Streptavidin Conjugates​
  • Streptavidin - DyLight 405
  • Streptavidin - DyLight 488
  • Streptavidin - DyLight 550
  • Streptavidin - DyLight 594
  • Streptavidin - DyLight 650
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Validated using strict quality standards
Quality is top priority and separates us from the rest.
We provide fully functional chemokines with the lowest endotoxin levels. 
​​All products are manufactured and tested in US.
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Cells expressing endogenous CXCR4 were stimulated with increasing concentrations of SDF-1α after a 90-minute incubation with calcium dye at 37oC.  The maximum response was plotted as a function of the ligand concentration.
Cells expressing recombinant CCR2 were assayed for migration through a transwell bare filter at various concentrations of MCP-3.  The responses are expressed as the % of total input cells.

Flow Cytometry with Biotinylated Chemokines 

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​A.  Uptake of 20nM CXCL12-biotin by U937 cells in the presence (red trace) and absence (cyan) of a CXCR4 inhibitor, AMD 3100.  U937 cells are not stained by streptavidin-PE in the absence of CXCL12-biotin (orange).
B.  Uptake of 20nM CCL2-biotin by THP1 cells (dark green trace) is abolished by the addition of CCL7 (orange) but not CCL14 (light green), suggesting a CCR2-specific internalization.  THP1 cells are not stained in the absence of CCL2-biotin (cyan).

Research Testimonials

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Research institutes using our chemokines

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CXCR4 X-Ray Crystal Structure PDB: 3ODU
Cold Spring Harbor Labs, NY, USA
Bristol Myers Squib, USA
Caltech, CA USA
Istituto Italiano di Tecnologia, Genova, Italy
UC San Diego, CA USA
Hannover Medical Center, Germany
UCSD Moores Cancer Center, CA USA
The Scripps Research Institute (TSRI) La Jolla, CA USA
University of Piedmont, Italy
Regeneron, USA
Sanford Consortium for Regenerative Medicine, CA USA
Genentech, USA
University of Utah, UT USA
University of Monash, Australia
University of Houston, TX USA
UC Berkley, CA USA
Tel Aviv University, Israel
Pfizer Global R & D, USA
University of Georgia, GA USA
NIBST, United Kingdom
Case Western Reserve University, USA
Merck Serono Geneva Research Center, Switzerland
Department of Veterans Affairs Medical Center, USA
Uppsala University, Sweden
Plus Many More

Fast World-Wide Shipping

For in-stock items US orders can receive shipments as soon as the next day or within 2-3 days for international orders. 

​We ship to Europe, Australia, and within the USA. 
Purchase directly from our product pages or request a quote. ​
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Request A QUote
Contact us at [email protected] ​for large scale and custom inquiries
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​ChemoTactics, Inc
6076 Corte del Cedro Carlsbad,
​CA 92011 USA
Phone: +1-(858)-412-0485
​Email: [email protected]
Chemokine Products
Biotinylated Chemokines
Unconjugated Chemokines
Streptavidin Conjugates
Research Services
Resources​
Published Applications
Protocols
​Blog
About
​
Contact
Made in the USA
  • Chemokine Products
    • Biotinylated Chemokines >
      • Biotinylated CCL2 (MCP-1)
      • Biotinylated CCL3 (MIP-1α)
      • Biotinylated CCL4 (MIP-1β)
      • Biotinylated CCL5 (Rantes)
      • Biotinylated CCL7 (MCP-3)
      • Biotinylated CCL14 (HCC-1)
      • Biotinylated CCL19 (MIP-3β)
      • Biotinylated CCL28 (MEC)
      • Biotinylated CXCL8 (IL-8)
      • Biotinylated CXCL12 (SDF-1α)
    • Unmodified Chemokines >
      • CCL2 (MCP-1)
      • CCL3 (MIP-1α)
      • CCL4 (MIP-1β)
      • CCL5 (RANTES)
      • CCL7 (MCP-3)
      • CCL14 (HCC-1)
      • CCL19 (MIP-3β)
      • CCL27 (CTACK)
      • CCL28 (MEC)
      • CXCL8 (IL-8)
      • CXCL10 (IP-10)
      • CXCL12 (SDF-1α)
  • Streptavidin Conjugates
  • Services
  • Resources
    • Published Applications Biotinylated CXCL12 and CCL5
    • What are Chemokines?
    • Chemokine Protocols >
      • Flow Cytometry with Biotinylated Chemokines
      • ELISA with Biotinylated Chemokines
      • Transwell Migration Assay
    • Blog
  • About
    • Contact