Recombinant Human Chemokines

High-quality recombinant human chemokines, produced in the US by researchers, for researchers. Our optimized recombinant system ensures the chemokines are native, retain endogenous functional activity, and have extremely low endotoxin levels. ​

Recombinant Human Chemokine Proteins

CCL2 (MCP-1)
​Monocyte Chemoattractant Protein-1
CCL3 (MIP-1a)
Macrophage Inflammatory
​Protein-1α
CCL4 (MIP-1B)
Macrophage Inflammatory
Protein-1beta
CCL5 (RANTES) 
Regulated on Activation, Normal T cell Expressed and Secreted ​
CCL7 (MCP-3)
​Monocyte
Chemotactic
​Protein 3
CCL14 (HCC-1)
​Hemofiltrate CC chemokine-1
CCL19 (MIP-3B)
Macrophage Inflammatory
Protein-3beta
CCL27 (CTACK)
Cutaneous T-cell-Attracting Chemokine
CCL28 (MEC)
Mucosae-associated Epithelial Chemokine
CXCL8 (IL-8)
​Interleukin 8
CXCL10 (IP-10)
10 kDa Interferon Gamma-Induced Protein
CXCL12 (SDF-1a)
Stromal-Cell
​Derived Factor-1a
These are all unlabeled chemokines click here for our biotinylated chemokines. 

We take custom size orders and protein expression projects.
Email us at [email protected] for more information.

Fast Shipping World-Wide

We ship priority overnight for in stock items which typically arrive next day for USA locations and 2-4 days for international. 
Publications with our Chemokines
  1. Pisani, A., Donno, R., Valenti, G., Pompa, P. P., Tirelli, N., & Bardi, G. (2022). Chemokine-decorated nanoparticles target specific subpopulations of primary blood mononuclear leukocytes. Nanomaterials, 12(20), 3560. https://doi.org/10.3390/nano12203560
  2. Pisani, A.; Donno, R.; Gennari, A.; Cibecchini, G.; Catalano, F.; Marotta, R.; Pompa, P.P.; Tirelli, N.; Bardi, G. CXCL12-PLGA/Pluronic Nanoparticle Internalization Abrogates CXCR4-Mediated Cell Migration. Nanomaterials 2020, 10, 2304. https://doi.org/10.3390/nano10112304
  3. Wang Z, Moresco P, Yan R, Li J, Gao Y, Biasci D, Yao M, Pearson J, Hechtman JF, Janowitz T, Zaidi R, Weiss MJ, Fearon DT. Carcinomas assemble a filamentous CXCL12-keratin-19 coating that suppresses T cell-mediated immune attack.  PNAS Jan 2022 Vol. 119 No. 4.  https://doi.org/10.1073/pnas.2119463119
  4. Chatterjee, T., Johnson-Buck, A. Walter, NG. Highly sensitive protein detection by aptamer-based single-molecule kinetic fingerprinting. Biosensors and Bioelectronics. Vol 216 15 Nov 2022. https://doi.org/10.1016/j.bios.2022.114639
  5. Zhikai Wang, Ran Yan, Jiayun Li, Ya Gao, Philip Moresco, Min Yao, Jaclyn F. Hechtman, Matthew J. Weiss, Tobias Janowitz, Douglas T. Fearon. Pancreatic cancer cells assemble a CXCL12-keratin 19 coating to resist immunotherapy. bioRxiv 776419; doi: https://doi.org/10.1101/776419. Posted: September 4, 2020
  6. Torretta S., Colombo G., Travelli C, Boumya S., Lim D., Genazzani A., Brolla A. The Cytokine Nicotinamide Phosphoribosyltransferase (eNAMPT; PBEF; Visfatin) Acts as a Natural Antagonist of C-C Chemokine Receptor Type 5 (CCR5). Cells 2020 Feb; 9(2):496. doi 10.3390/cells9020496 PMID: 32098202
  7. Wu, B., Chien, E.Y., Mol, C.D., Fenalti, G., Liu, W., Katritch, V., Abagyan, R., Brooun, A., Wells, P., Bi, F.C., Hamel, D.J., Kuhn, P., Handel, T.M., Cherezov, V., Stevens, R.C. Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists.  Science, 2010. 330: 1066-1071. PMID: 20929726
  8. Ervin E. Kara, Iain Comerford, Cameron R. Bastow, Kevin A. Fenix, Wendel Litchfield, Tracey M. Handel, and Shaun R. McColl.  Distinct chemokine receptor axes regulate T helper 9 cell trafficking to allergic and autoimmune inflammatory sites. J Immunol., 191:1110-1117, 2013. PMID: 23797668
  9. M. O'Hayre, C.L. Salanga, T.J. Kipps, D. Messmer, P.C. Dorrestein, T.M. Handel (2010) Elucidating the CXCL12/CXCR4 Signaling Network in Chronic Lymphocytic Leukemia through Phosphoproteomic Analysis. PLoS One. 5:e11716. PMID: 20661426
  10. T.M. Handel, Z. Johnson, M. Mack, R. Cirillo, V. Muzio, M. Teixiera, M. Déruaz, F. Borlat, T.N.C. Wells, and A.E.I. Proudfoot (2008). An Engineered Monomer of CCL2 has Anti-inflammatory Properties Emphasizing the Importance of Oligomerization for Chemokine Activity In Vivo. J Leukocyte Biology. 84(4):1101-8. PMID: 18662971​
Made in the USA